Mobic (meloxicam) is a prescription nonsteroidal anti-inflammatory drug (NSAID) specifically formulated to manage pain and inflammation associated with osteoarthritis and rheumatoid arthritis. As a selective COX-2 inhibitor, it offers targeted relief with a potentially improved gastrointestinal tolerability profile compared to some traditional NSAIDs. This medication works by reducing hormones that cause inflammation and pain in the body, providing patients with sustained comfort and improved mobility. It is available in tablet and oral suspension forms, allowing for flexible dosing under medical supervision.

Features

• Active ingredient: Meloxicam
• Drug class: Nonsteroidal anti-inflammatory drug (NSAID), selective COX-2 inhibitor
• Available formulations: 7.5 mg and 15 mg tablets; 7.5 mg/5 mL oral suspension
• Administration: Oral, once daily
• Prescription status: Rx-only medication
• Mechanism: Inhibits prostaglandin synthesis via cyclooxygenase-2 (COX-2) enzyme suppression

Benefits

• Provides effective relief from chronic arthritis pain and inflammation
• Enables improved joint mobility and daily functioning
• Offers convenient once-daily dosing for consistent therapeutic coverage
• Demonstrates selective COX-2 inhibition for potentially reduced gastrointestinal side effects
• Supports long-term management of inflammatory arthritis conditions
• Helps maintain quality of life through sustained pain control

Common use

Mobic is primarily prescribed for the relief of signs and symptoms of osteoarthritis and rheumatoid arthritis in adults. It is indicated for the management of pain, stiffness, and inflammation associated with these degenerative joint conditions. Healthcare providers may also consider its use for other inflammatory conditions where NSAID therapy is appropriate, though such use would be off-label and requires careful medical evaluation. The medication is not recommended for acute pain management or for use in pediatric patients.

Dosage and direction

The recommended initial dose for osteoarthritis is 7.5 mg taken once daily. For rheumatoid arthritis, the recommended dose is 15 mg once daily. The maximum recommended daily dose is 15 mg regardless of indication. Tablets should be taken with a full glass of water, with or without food, though taking with food may reduce the potential for stomach upset. The oral suspension should be shaken well before each use and measured with the provided dosing syringe. Dosage adjustments may be necessary for elderly patients, those with renal impairment, or those taking concomitant medications that affect meloxicam metabolism.

Precautions

Patients should inform their healthcare provider of any history of cardiovascular disease, hypertension, gastrointestinal disorders, liver or kidney disease, asthma, or bleeding disorders. Regular monitoring of blood pressure, renal function, and hemoglobin levels may be necessary during treatment. Use with caution in patients with dehydration, as NSAIDs may impair renal function. Avoid alcohol consumption during therapy as it may increase the risk of gastrointestinal bleeding. Patients should report any signs of bleeding, unusual weight gain, or edema promptly to their physician.

Contraindications

Mobic is contraindicated in patients with known hypersensitivity to meloxicam or any components of the formulation. It should not be used in patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Contraindicated in the setting of coronary artery bypass graft (CABG) surgery. Should not be used in patients with active peptic ulcer disease or gastrointestinal bleeding. Not recommended for patients with severe hepatic impairment or advanced renal disease. Avoid use during the third trimester of pregnancy.

Possible side effects

Common side effects may include gastrointestinal symptoms such as dyspepsia, nausea, abdominal pain, diarrhea, and flatulence. Other frequently reported effects include dizziness, headache, and peripheral edema. Serious side effects requiring immediate medical attention include signs of gastrointestinal bleeding (black tarry stools, vomiting blood), chest pain, shortness of breath, weakness on one side of the body, slurred speech, swelling of face or throat, skin rash, jaundice, or decreased urine output. Long-term use may increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke.

Drug interaction

Meloxicam may interact with anticoagulants (warfarin), antiplatelet agents, selective serotonin reuptake inhibitors (SSRIs), and other NSAIDs, increasing bleeding risk. Concomitant use with ACE inhibitors, angiotensin receptor blockers, or diuretics may reduce antihypertensive effects and worsen renal function. May increase lithium levels and methotrexate toxicity. CYP2C9 inhibitors may increase meloxicam concentrations. Aspirin coadministration may decrease meloxicam levels and increase gastrointestinal toxicity. Corticosteroids may potentiate gastrointestinal ulcer risk.

Missed dose

If a dose is missed, take it as soon as remembered unless it is almost time for the next scheduled dose. Do not double the dose to make up for a missed one. If multiple doses are missed, contact your healthcare provider for guidance on resuming therapy. Maintain regular dosing schedule to ensure consistent therapeutic levels. Patients should not adjust their dosing regimen without medical consultation.

Overdose

Symptoms of overdose may include lethargy, drowsiness, nausea, vomiting, epigastric pain, gastrointestinal bleeding, hypertension, acute renal failure, respiratory depression, and coma. In case of suspected overdose, seek immediate medical attention. There is no specific antidote for meloxicam overdose. Management is supportive and symptomatic, including gastric lavage if presented early, activated charcoal administration, and careful monitoring of vital signs, renal function, and electrolyte balance. Hemodialysis is not effective due to high protein binding.

Storage

Store at room temperature (20-25°C or 68-77°F) in the original container, protected from light and moisture. Keep the bottle tightly closed when not in use. Do not freeze the oral suspension. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging. Properly discard any unused medication after treatment completion according to local regulations or medication take-back programs.

Disclaimer

This information is provided for educational purposes only and does not constitute medical advice. Mobic is a prescription medication that should be used only under the supervision of a qualified healthcare professional. Individual response to therapy may vary. Patients should consult their healthcare provider for personalized medical advice, including proper diagnosis, treatment options, and monitoring requirements. Never disregard professional medical advice or delay seeking it because of information contained herein.

Reviews

Clinical studies demonstrate that Mobic provides effective pain relief and improved physical function in patients with osteoarthritis and rheumatoid arthritis. Many patients report significant improvement in morning stiffness and joint mobility. Healthcare providers note its favorable efficacy-to-tolerability ratio compared to some traditional NSAIDs. Some patients experience gastrointestinal side effects, though often less severe than with non-selective NSAIDs. Long-term users appreciate the once-daily dosing convenience. Medical professionals emphasize the importance of regular monitoring and appropriate patient selection for optimal outcomes.