MaxGun Sublingual Spray: Rapid-Acting Nitroglycerin for Angina Relief
| Product dosage: 10 ml | |||
|---|---|---|---|
| Package (num) | Per sprayer | Price | Buy |
| 5 | $15.48 | $77.40 (0%) | 🛒 Add to cart |
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| 10 | $12.47
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MaxGun Sublingual Spray is a prescription medication formulated for the acute relief of angina pectoris attacks or their prophylaxis. It contains nitroglycerin, a potent vasodilator that acts on vascular smooth muscle to rapidly reduce cardiac preload and afterload, thereby decreasing myocardial oxygen demand and relieving anginal symptoms. This metered-dose spray offers a modern, precise, and convenient alternative to traditional sublingual tablets, ensuring consistent dosing and stability. It is designed for use in adults with a established diagnosis of coronary artery disease and is intended for sublingual or buccal administration, providing therapeutic effects within minutes. Clinical use should always be guided by a comprehensive cardiovascular treatment plan under physician supervision.
Features
- Contains nitroglycerin 0.4 mg per metered spray
- Alcohol-free, sugar-free formulation
- Delivers 200 consistent doses per canister
- Designed for sublingual or buccal mucosal absorption
- Portable, pressurized canister with protective dust cap
- Stable at room temperature; does not require refrigeration
- Rapid onset of action, typically within 1–3 minutes
- Precisely calibrated metering valve for accurate dosing
Benefits
- Provides rapid symptomatic relief during acute angina episodes
- Reduces myocardial oxygen demand through venodilation and arterial relaxation
- May be used prophylactically to prevent angina triggered by predictable exertion
- Offers improved stability and convenience compared to sublingual tablets
- Enables precise dosing without degradation from handling or moisture
- Facilitates administration in patients with dry mouth or difficulty dissolving tablets
Common use
MaxGun Sublingual Spray is indicated for acute relief of angina pectoris attacks in patients with coronary artery disease. It is also used prophylactically immediately prior to situations likely to provoke anginal episodes, such as physical exertion, emotional stress, or exposure to cold. The spray is not intended for routine chronic therapy to prevent angina but rather for as-needed management of acute symptoms. Its use should be part of a comprehensive anti-anginal regimen that may include long-acting nitrates, beta-blockers, calcium channel blockers, and lifestyle modifications.
Dosage and direction
Administer one metered spray (0.4 mg) onto or under the tongue at the onset of an anginal attack. Do not inhale the spray. The mouth should be closed immediately after administration, and the patient should avoid swallowing for 30–60 seconds to facilitate mucosal absorption. If relief is not achieved within 5 minutes, a second dose may be administered. If symptoms persist after three doses within 15 minutes, seek emergency medical attention immediately. For prophylactic use, administer one spray 5–10 minutes prior to anticipated exertion or stress. The minimum effective dose should be used; tolerance may develop with frequent use.
Precautions
Patients should be seated when using nitroglycerin to minimize the risk of hypotension and syncope. Use with caution in patients with hypovolemia, hypotension, or inferior wall myocardial infarction involving right ventricular involvement. Headache is common and may be treated with analgesics; it often diminishes with continued use. Avoid sudden discontinuation after chronic use to prevent rebound angina. Periodic reassessment of anti-anginal therapy is recommended. Store away from heat and open flame; the container is pressurized.
Contraindications
MaxGun Subherbal Spray is contraindicated in patients with known hypersensitivity to nitroglycerin or other nitrates/nitrites. It must not be used in patients with severe anemia, increased intracranial pressure, or uncorrected hypovolemia. Concomitant use with phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil, vardenafil) is absolutely contraindicated due to risk of severe hypotension. Not for use in patients with cardiogenic shock or marked hypotension (systolic BP <90 mmHg).
Possible side effects
- Headache (most common, often dose-related)
- Dizziness, lightheadedness, or syncope
- Reflex tachycardia
- Flushing or feeling of warmth
- Nausea or vomiting
- Hypotension
- Paradoxical bradycardia in some cases
- Local irritation or burning sensation at administration site
Drug interaction
Concomitant use with phosphodiesterase-5 inhibitors (e.g., sildenafil) can cause life-threatening hypotension. Additive hypotensive effects may occur with other vasodilators, antihypertensives, calcium channel blockers, beta-blockers, alcohol, or tricyclic antidepressants. Aspirin may increase nitroglycerin bioavailability. Ergot alkaloids may antagonize vasodilatory effects. Heparin effect may be reduced. Always inform healthcare providers of all medications being taken.
Missed dose
As MaxGun is used on an as-needed basis for acute angina relief, the concept of a “missed dose” does not apply. It is not scheduled for regular administration. If an anginal episode occurs and is not treated, follow emergency protocols as directed by your physician.
Overdose
Symptoms of overdose include severe hypotension, throbbing headache, dizziness, palpitations, visual disturbances, nausea, vomiting, syncope, cyanosis, dyspnea, and methemoglobinemia (evidenced by chocolate-brown blood and hypoxia unresponsive to oxygen). Management includes placing patient in Trendelenburg position, administering IV fluids, and considering alpha-adrenergic agonists if needed. Methylene blue may be used for methemoglobinemia. Hemodialysis is not effective.
Storage
Store at controlled room temperature (20°–25°C or 68°–77°F). Do not freeze. Keep canister away from open flame or excessive heat (may cause bursting). Do not puncture or incinerate. Keep tightly closed with dust cap in place. Discard 3 months after first use, even if not empty, to ensure potency and sterility. Keep out of reach of children.
Disclaimer
This information is for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. Do not disregard professional medical advice or delay seeking it based on this content. Use only as prescribed.
Reviews
“As a cardiologist, I find the metered spray offers more reliable dosing than tablets, especially in elderly patients with dry mouth. Onset is consistently rapid.” — Dr. A. Reynolds, MD
“After switching from tablets, I appreciate the stability and portability. The spray works within two minutes during my walks.” — Patient, 68
“Clinical trials demonstrate bioequivalence to sublingual tablets with improved dose consistency. A valuable option in angina management.” — Clinical Pharmacologist