Levitra Extra Dosage (vardenafil hydrochloride) represents a high-potency pharmaceutical option specifically formulated for men with severe erectile dysfunction (ED) or those who have demonstrated inadequate response to standard-dose PDE5 inhibitors. As a prescription medication, it contains an elevated concentration of vardenafil, designed to enhance blood flow to the penile tissues, thereby facilitating a firm and sustainable erection when combined with sexual stimulation. This formulation is intended for use under strict medical supervision, following a comprehensive evaluation of cardiovascular health and individual therapeutic needs. Its advanced pharmacokinetic profile ensures targeted action, making it a pivotal option in urological and andrological practice for challenging cases of ED.

Features

• Active ingredient: Vardenafil hydrochloride 20 mg
• Pharmaceutical class: Phosphodiesterase type 5 (PDE5) inhibitor
• Onset of action: As early as 25–60 minutes post-administration
• Duration of efficacy: Up to 5–8 hours
• Administration: Oral tablet, taken with or without food (avoid high-fat meals)
• Available in film-coated tablets for optimized dissolution

Benefits

• Provides a robust therapeutic option for patients with severe erectile dysfunction unresponsive to lower doses.
• Offers an extended window of efficacy, allowing for greater spontaneity in sexual activity.
• Enhances nitric oxide-mediated vasodilation specifically in the corpus cavernosum, supporting physiological erection mechanisms.
• Demonstrates high selectivity for PDE5 enzymes, minimizing off-target effects.
• Supported by clinical data showing improved erectile function scores in refractory populations.
• May contribute to improved self-esteem and relationship satisfaction when used as part of a comprehensive ED management plan.

Common use

Levitra Extra Dosage is prescribed for the treatment of erectile dysfunction in adult men. It is specifically indicated for individuals who have not achieved satisfactory results with standard-dose vardenafil or other PDE5 inhibitors. It is not intended for use in women, adolescents, or men without erectile dysfunction. The medication requires sexual stimulation to produce its intended effect and does not increase libido.

Dosage and direction

The recommended dose is one 20 mg tablet taken orally approximately 25–60 minutes before anticipated sexual activity. Do not exceed one dose within a 24-hour period. Tablets should be swallowed whole with a glass of water; crushing or splitting is not advised. Dosage adjustments may be necessary for patients with hepatic impairment, severe renal impairment (CrCl < 30 mL/min), or those taking certain concomitant medications. Always follow the prescribing physician’s instructions.

Precautions

• Prior to initiation, patients should undergo a thorough cardiovascular assessment due to the potential for cardiac risk during sexual activity.
• Use with caution in patients with anatomical penile deformities, bleeding disorders, or active peptic ulceration.
• Avoid use in patients with hereditary degenerative retinal disorders.
• Not recommended for use with other erectile dysfunction treatments.
• May cause hypotension; caution advised in patients using antihypertensives.
• Advise patients to avoid excessive alcohol consumption, which may increase risk of adverse effects.

Contraindications

• Concomitant use with nitrates or nitric oxide donors in any form.
• History of hypersensitivity to vardenafil or any component of the formulation.
• Patients with severe hepatic impairment (Child-Pugh C).
• Concurrent use with potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir).
• Unstable angina, recent myocardial infarction, or life-threatening arrhythmias.

Possible side effects

Common adverse reactions (≥2%) include headache, flushing, dyspepsia, nasal congestion, and dizziness. Less frequently reported effects include visual disturbances (e.g., cyanopsia), back pain, myalgia, and nausea. Rare but serious side effects may include priapism, sudden hearing loss, non-arteritic anterior ischemic optic neuropathy (NAION), and cardiovascular events. Seek immediate medical attention for erections lasting more than 4 hours or sudden vision/hearing changes.

Drug interaction

• Nitrates: Concomitant use is contraindicated due to risk of severe hypotension.
• Alpha-blockers: May potentiate hypotensive effects; avoid concurrent use.
• CYP3A4 inhibitors (e.g., erythromycin, clarithromycin): Increase vardenafil exposure; dose adjustment required.
• CYP3A4 inducers (e.g., rifampin): May reduce efficacy.
• Antihypertensives: Additive blood pressure-lowering effects possible.
• Grapefruit juice: May increase plasma concentrations; avoid consumption.

Missed dose

Levitra Extra Dosage is taken on an as-needed basis. There is no scheduled dosing regimen; therefore, the concept of a “missed dose” does not apply. Do not take extra tablets to make up for a missed opportunity.

Overdose

In case of suspected overdose, seek immediate medical attention. Symptoms may include severe headache, visual disturbances, syncope, prolonged erection, and hypotension. Standard supportive measures should be employed; haemodialysis is unlikely to be effective due to high protein binding.

Storage

Store at room temperature (15–30°C) in the original container. Protect from light and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.

Disclaimer

This information is intended for educational purposes and does not replace professional medical advice. Levitra Extra Dosage is a prescription medication and should only be used under the supervision of a qualified healthcare provider. Individual results may vary. Always consult with a physician for diagnosis and treatment recommendations tailored to your specific health status.

Reviews

Clinical studies and post-marketing surveillance indicate high patient satisfaction among men with previously treatment-resistant erectile dysfunction. Many users report improved erectile function and successful intercourse attempts. However, individual experiences may vary based on underlying health conditions, adherence to dosing instructions, and psychological factors. Always discuss your experience with your prescribing physician to optimize therapeutic outcomes.