Bactroban Ointment 5g contains the antibacterial agent mupirocin, formulated specifically for topical application to combat localized skin infections caused by susceptible strains of bacteria, particularly Staphylococcus aureus and Streptococcus pyogenes. As a prescription medication, it represents a first-line therapeutic option for impetigo and other primary skin infections, offering concentrated antibacterial action directly at the site of infection. Its ointment base ensures optimal delivery of the active ingredient while providing a protective barrier to support the healing process.

Features

• Contains 2% mupirocin calcium equivalent to 2.15% mupirocin
• Net content: 5 grams per tube
• White, opaque, hydrophilic petroleum-based ointment
• Prescription-only medication
• Bactericidal action through inhibition of bacterial isoleucyl-tRNA synthetase
• Effective against gram-positive bacteria including methicillin-resistant S. aureus (MRSA) in some cases
• Water-miscible base for easy application and removal

Benefits

• Rapidly targets and eliminates bacterial pathogens at the infection site
• Reduces risk of infection spread to surrounding tissues or other individuals
• Minimizes systemic antibiotic exposure and associated side effects
• Supports natural healing processes while preventing bacterial colonization
• Convenient topical application with precise dosing control
• Effective against some antibiotic-resistant strains when used appropriately

Common use

Bactroban Ointment is primarily indicated for the topical treatment of impetigo caused by Staphylococcus aureus and Streptococcus pyogenes. It is also used for secondary infected traumatic skin lesions. Healthcare providers may prescribe it for other localized skin infections where the causative organisms are known to be susceptible to mupirocin. The ointment is particularly valuable in cases where systemic antibiotics might be unnecessary or where targeted therapy is preferred to minimize systemic exposure.

Dosage and direction

Apply a small amount of ointment to the affected area three times daily. The area may be covered with a gauze dressing if desired. Wash hands before and after application unless hands are the treatment area. For impetigo, treatment typically continues for 7-10 days. The affected area should be gently cleaned and dried before application. Use exactly as prescribed by your healthcare provider; do not exceed recommended frequency or duration of application.

Precautions

Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not use on large open wounds or severe burns without medical supervision. Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. If irritation or allergic reaction develops, discontinue use and consult your physician. Use with caution in patients with moderate or severe renal impairment. Not for ophthalmic, intranasal, or intravaginal use.

Contraindications

Hypersensitivity to mupirocin or any component of the formulation. The ointment should not be used in patients with known hypersensitivity to polyethylene glycol, as this may cause irritation. Avoid use in cases where the infection involves deep tissues, abscesses, or requires surgical intervention. Not recommended for use in the nasal passages unless specifically formulated for nasal application (separate product available).

Possible side effects

Common side effects may include burning, stinging, or pain at the application site (occurring in approximately 3% of patients). Less frequently reported effects include itching (1.6%), rash (1.5%), nausea (1.2%), and dry skin. Rare cases of contact dermatitis, erythema, and generalized skin reactions have been reported. Systemic absorption is minimal with topical application, but allergic reactions including anaphylaxis, though extremely rare, have been documented.

Drug interaction

Formal drug interaction studies have not been conducted with topical mupirocin. However, concurrent use with other topical products may alter absorption characteristics or cause physical incompatibility. Avoid applying other topical medications to the same site unless directed by a healthcare provider. The polyethylene glycol base could theoretically enhance the absorption of other topical agents. No known interactions with systemic medications have been established.

Missed dose

Apply the missed dose as soon as remembered, unless it is almost time for the next scheduled application. Do not double the dose to make up for a missed application. Maintain the regular dosing schedule. If multiple doses are missed, contact your healthcare provider for guidance on whether to extend the treatment duration.

Overdose

Topical overdose is unlikely due to minimal systemic absorption. However, excessive application could potentially increase the risk of local adverse effects. If accidental ingestion occurs, seek medical attention immediately. Symptoms of ingestion may include gastrointestinal upset. Dialysis is not expected to enhance elimination of mupirocin due to high protein binding.

Storage

Store at room temperature between 20°C to 25°C (68°F to 77°F). Excursions permitted between 15°C to 30°C (59°F to 86°F). Do not freeze. Keep tube tightly closed when not in use. Protect from excessive heat and direct sunlight. Keep out of reach of children and pets. Discard any unused product after the completion of therapy or after the expiration date printed on the packaging.

Disclaimer

This information is provided for educational purposes only and does not replace professional medical advice. Always consult with a qualified healthcare provider for diagnosis and treatment recommendations. Individual response to medication may vary. The prescribing physician should be informed of all medical conditions and concurrent medications. Proper diagnosis of the infection type and causative organism is essential before initiating therapy.

Reviews

Clinical studies demonstrate Bactroban Ointment achieves clinical success rates of 85-95% in treating impetigo when caused by susceptible organisms. Dermatologists consistently report high satisfaction with its efficacy profile and low incidence of adverse effects. Patients appreciate the convenience of topical application and minimal systemic side effects. Many clinical guidelines recommend mupirocin ointment as first-line therapy for localized skin infections where topical treatment is appropriate.