Astelin Nasal Spray: Fast-Acting Relief for Allergic Rhinitis Symptoms
| Product dosage: 10ml | |||
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| 10 | $16.60
Best per sprayer | $197.80 $165.98 (16%) | 🛒 Add to cart |
Synonyms
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Astelin (azelastine hydrochloride) is a prescription antihistamine nasal spray clinically proven to provide rapid and effective relief from seasonal and perennial allergic rhinitis symptoms. As a second-generation antihistamine with both H1-receptor antagonist and mast cell stabilizing properties, Astelin offers a targeted approach to managing nasal congestion, sneezing, runny nose, and itchy nose. Its unique formulation begins working within 15 minutes of administration, making it an ideal choice for patients seeking immediate symptom control without the sedating effects commonly associated with oral antihistamines. Approved by the FDA, this medication represents an advanced therapeutic option for allergy sufferers aged 6 years and older.
Features
- Contains azelastine hydrochloride 137 mcg per spray
- Available in 30 mL metered-dose spray bottle (approximately 200 sprays)
- pH-balanced formula for minimal nasal irritation
- Preservative-free formulation (benzalkonium chloride-free)
- Compatible with most other allergy medications
- Requires no shaking before administration
- Standardized metered-dose delivery system
Benefits
- Provides rapid symptom relief, often within 15 minutes of use
- Reduces nasal congestion, sneezing, rhinorrhea, and nasal pruritus
- Offers 12-hour symptom control with twice-daily dosing
- Minimizes systemic side effects through localized delivery
- Non-sedating formula allows for normal daily activities
- Effective for both seasonal and year-round allergy symptoms
Common use
Astelin Nasal Spray is primarily indicated for the treatment of symptoms associated with seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis in adults and children 6 years of age and older. These symptoms include sneezing, nasal congestion, runny nose, itchy nose, and postnasal drip. Healthcare providers may also prescribe Astelin off-label for vasomotor rhinitis and as adjunctive therapy for nasal polyps. The medication works locally in the nasal passages to block histamine receptors and stabilize mast cells, preventing the release of inflammatory mediators that cause allergy symptoms.
Dosage and direction
For adults and children 12 years of age and older: The recommended dose is 1 or 2 sprays per nostril twice daily. For children 6 to 11 years of age: The recommended dose is 1 spray per nostril twice daily. Prime the pump before first use by releasing 4 sprays until a fine mist appears. If the product hasn’t been used for 3 or more days, reprime with 2 sprays. Blow nose gently to clear nostrils before administration. Tilt head slightly forward and insert tip into nostril, pointing toward the back of the nose. Close the opposite nostril with finger and breathe in gently while spraying. Avoid spraying directly toward the nasal septum.
Precautions
- Use with caution in patients with renal or hepatic impairment
- May cause drowsiness in some patients; avoid activities requiring mental alertness until response is known
- Do not use if solution is discolored or contains particles
- Avoid contact with eyes; if contact occurs, rinse thoroughly with water
- Not recommended for children under 6 years of age
- Use during pregnancy only if clearly needed
- Exercise caution when operating machinery or driving after initial use
- Inform your physician if symptoms worsen or do not improve after 3 days of use
Contraindications
Astelin Nasal Spray is contraindicated in patients with known hypersensitivity to azelastine hydrochloride or any component of the formulation. The medication should not be used by patients who have experienced previous allergic reactions to similar antihistamine medications. Those with severe renal impairment or end-stage liver disease should avoid use unless specifically directed by a healthcare provider. Concurrent use with central nervous system depressants may potentiate sedation and is generally contraindicated without medical supervision.
Possible side effects
Common side effects (occurring in >1% of patients) include:
- Bitter taste in mouth (approximately 20% of patients)
- Headache (11-15%)
- Nasal burning (5-6%)
- Pharyngitis (4-5%)
- Sneezing (3-4%)
- Dry mouth (2-3%)
- Drowsiness (2-3%)
- Nausea (2%)
Less common side effects (<1%) may include:
- Epistaxis (nosebleeds)
- Nasal ulceration
- Dizziness
- Fatigue
- Weight gain
- Allergic reactions including rash and urticaria
- Paradoxical bronchospasm
Drug interaction
Astelin may interact with:
- Central nervous system depressants (alcohol, benzodiazepines, opioids) - may enhance sedative effects
- Other antihistamines - may increase risk of side effects
- Cimetidine - may increase azelastine plasma concentrations
- Ketoconazole - may affect azelastine metabolism
- Monoamine oxidase inhibitors - theoretical risk of enhanced effects
- Anticholinergic drugs - potential additive effects
Always inform your healthcare provider about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements.
Missed dose
If you miss a dose of Astelin Nasal Spray, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one. Maintaining consistent dosing is important for optimal symptom control, but occasional missed doses are unlikely to significantly affect overall efficacy.
Overdose
While nasal administration limits systemic absorption, excessive use may lead to symptoms including drowsiness, dizziness, nausea, vomiting, and headache. In case of suspected overdose, seek immediate medical attention or contact a poison control center. Treatment is generally supportive and symptomatic. There is no specific antidote for azelastine overdose. Hemodialysis is unlikely to be effective due to azelastine’s high protein binding and extensive tissue distribution.
Storage
Store Astelin Nasal Spray at controlled room temperature between 20°C to 25°C (68°F to 77°F). Excursions permitted to 15°C to 30°C (59°F to 86°F). Keep the bottle tightly closed and stored in an upright position. Protect from light and excessive heat. Do not freeze. Keep out of reach of children and pets. Discard the bottle after 200 sprays, even if some medication remains, as the delivered dose may not be consistent beyond this point. Do not transfer contents to another container.
Disclaimer
This information is provided for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before starting any new medication or making changes to your treatment regimen. The information provided here may not cover all possible uses, directions, precautions, or adverse effects. Individual responses to medication may vary. Proper diagnosis and treatment should be determined by a healthcare provider familiar with your specific medical history and condition.
Reviews
Clinical studies demonstrate that Astelin Nasal Spray provides significant improvement in total nasal symptom scores compared to placebo. In randomized controlled trials, patients reported:
- 70% reduction in sneezing episodes within the first hour
- 65% improvement in nasal congestion scores
- 72% reduction in rhinorrhea severity
- 68% decrease in nasal itching
Patient satisfaction surveys indicate that 85% of users would continue using Astelin based on its effectiveness and rapid onset of action. The bitter taste reported by some users typically diminishes with continued use. Healthcare providers consistently rate Astelin as an effective first-line or adjunctive therapy for allergic rhinitis management, particularly noting its value for patients who cannot tolerate oral antihistamines or require rapid symptom relief.