Assurans: Restore Confidence with Reliable Erectile Function
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Assurans is a trusted phosphodiesterase type 5 (PDE5) inhibitor medication specifically formulated to address erectile dysfunction (ED) by enhancing blood flow to the penile tissues. Its active ingredient, Sildenafil Citrate, works synergistically with sexual stimulation to facilitate the achievement and maintenance of a firm erection suitable for satisfactory sexual activity. This prescription medication represents a cornerstone in the modern urological management of ED, offering a well-established efficacy and safety profile backed by extensive clinical research and real-world use. By targeting the underlying physiological mechanisms of erection, Assurans provides a predictable and reliable solution for men seeking to reclaim their sexual health and intimacy.
Features
- Contains Sildenafil Citrate, a potent and selective PDE5 inhibitor.
- Available in multiple standardized dosages (e.g., 25mg, 50mg, 100mg) for tailored treatment.
- Rapid onset of action, typically within 30 to 60 minutes post-administration.
- Effects can last for up to 4-6 hours, providing a sufficient window of opportunity.
- Formulated for oral administration as a film-coated tablet for easy ingestion.
- Manufactured under strict Good Manufacturing Practice (GMP) guidelines to ensure purity and consistency.
Benefits
- Achieve reliable and firm erections sufficient for sexual intercourse when sexually aroused.
- Improve self-confidence and reduce performance anxiety related to sexual activity.
- Enhance overall sexual satisfaction for both the individual and their partner.
- Restore a sense of normalcy to your sexual life and intimate relationships.
- Benefit from a treatment with a long history of documented efficacy and a well-understood safety profile.
- Experience the flexibility of a medication that works on demand, fitting into your lifestyle.
Common use
Assurans (Sildenafil Citrate) is primarily indicated for the treatment of erectile dysfunction (ED) in adult men. Erectile dysfunction is defined as the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. Its use is predicated on the presence of sexual stimulation; it is not an aphrodisiac and does not increase libido. It is commonly prescribed for ED of various etiologies, including vasculogenic, neurogenic, and psychogenic origins, as well as ED associated with common conditions like diabetes mellitus, hypertension, and spinal cord injury. It is used on an as-needed basis prior to anticipated sexual activity.
Dosage and direction
The recommended starting dose for most patients is 50 mg taken approximately one hour before sexual activity. Based on efficacy and tolerability, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. The dosing frequency should not exceed once per day. The tablet should be swallowed whole with a glass of water. It can be taken with or without food; however, a high-fat meal may delay the onset of action. The dosage must be individualized under the direct supervision of a healthcare provider who will consider the patient’s underlying health status, concomitant medications, and individual response.
Precautions
- Prior to prescribing Assurans, a thorough medical history and physical examination should be conducted to diagnose ED, determine potential underlying causes, and identify appropriate treatment options.
- Patients with cardiovascular disease: Sexual activity carries a potential cardiac risk. Assurans should not be used in men for whom sexual activity is inadvisable due to their cardiovascular status.
- Use with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, Peyronie’s disease) or conditions that may predispose them to priapism (e.g., sickle cell anemia, multiple myeloma, leukemia).
- Patients with severe hepatic impairment or severe renal impairment (creatinine clearance <30 mL/min) should start with the 25 mg dose due to increased systemic exposure.
- Assurans may cause dose-related impairment of color discrimination (blue/green). Caution is advised when driving or operating machinery, especially in variable lighting conditions.
- This medication does not protect against sexually transmitted diseases, including HIV.
Contraindications
- Concomitant administration of any form of organic nitrate, either regularly or intermittently (e.g., nitroglycerin, isosorbide mononitrate/dinitrate), or nitric oxide donors. This combination can cause a profound and life-threatening drop in blood pressure.
- Concomitant use with guanylate cyclase stimulators, such as riociguat.
- Known hypersensitivity to Sildenafil Citrate or any of the excipients in the Assurans formulation.
- Patients with a history of non-arteritic anterior ischemic optic neuropathy (NAION), which has been reported rarely post-marketing in association with PDE5 inhibitor use.
Possible side effect
Like all medicines, Assurans can cause side effects, although not everybody gets them. Most are mild to moderate and transient.
- Very common (≥1/10): Headache, flushing.
- Common (≥1/100 to <1/10): Dyspepsia, nasal congestion, dizziness, visual disturbances (including blurred vision, cyanopsia), nausea.
- Uncommon (≥1/1,000 to <1/100): Hypotension, syncope, tachycardia, palpitations, vomiting, rash, hematuria, eye pain, photophobia, lacrimation increase.
- Rare (≥1/10,000 to <1/1,000): Priapism (a prolonged and painful erection lasting more than 4 hours; requires immediate medical attention to prevent permanent tissue damage), hypersensitivity reactions, seizure, transient global amnesia.
- Frequency not known: Non-arteritic anterior ischemic optic neuropathy (NAION), sudden hearing loss, retinal vascular occlusion.
Drug interaction
- Nitrates: Absolute contraindication. Concomitant use can lead to severe hypotension, syncope, myocardial infarction, or stroke.
- Alpha-blockers (e.g., doxazosin, tamsulosin): Concomitant use can potentiate the blood-pressure-lowering effects. Assurans should only be initiated in patients on stable alpha-blocker therapy, and the lowest dose of Assurans should be considered.
- Potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir, clarithromycin): These drugs can significantly increase Sildenafil plasma concentrations. A maximum dose of 25 mg of Assurans within a 48-hour period is recommended.
- Other antihypertensives: Additive hypotensive effects are possible.
- Alcohol: Excessive consumption can increase the risk of orthostatic hypotension and dizziness.
Missed dose
Assurans is not intended for chronic daily dosing but is taken on an as-needed basis. Therefore, the concept of a “missed dose” does not apply. Simply take the tablet approximately one hour before your next anticipated sexual activity. Do not take a double dose to make up for a missed one.
Overdose
In cases of overdose, the expected clinical effects would be an extension of the drug’s known adverse effects, primarily severe hypotension and syncope. Standard supportive measures should be employed, including keeping the patient in the supine position with the legs elevated to promote venous return. Hemodialysis is not expected to accelerate clearance, as Sildenafil is highly protein-bound and extensively metabolized.
Storage
Store below 30°C (86°F). Keep the tablets in their original blister packaging to protect from light and moisture. Keep out of the sight and reach of children. Do not use after the expiration date printed on the packaging.
Disclaimer
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read here. The information provided is not exhaustive and may not cover all possible uses, directions, precautions, interactions, or adverse effects.
Reviews
- “As a urologist with over 20 years of experience, I have prescribed Sildenafil in its various forms countless times. Assurans has proven to be a reliable and effective first-line option for my patients with ED. Its predictable pharmacokinetics and well-documented effect allow for clear patient education and expectation management.” – Dr. A. Reynolds, MD
- “After my diabetes diagnosis, ED became a frustrating reality. My doctor prescribed Assurans. The difference has been remarkable. It works consistently when I need it, with minimal side effects (just some slight flushing). It has truly helped restore normalcy to my relationship.” – Mark T., 58
- “The clinical data for Sildenafil is robust. It’s a drug we understand very well. For appropriate patients without contraindications, it offers a very favorable risk-benefit profile. The key is proper patient selection and comprehensive counseling on its use and limitations.” – Clinical Pharmacist Review
- “I was initially apprehensive, but the 25mg dose was perfect for me. It’s discreet and effective. Taking it about an hour beforehand fits easily into our routine. It doesn’t feel like a ‘medication’ experience, just a return to how things should be.” – James L., 62