Malegra FXT Plus is a clinically-formulated combination medication designed to address two of the most prevalent male sexual health concerns simultaneously: erectile dysfunction and premature ejaculation. By integrating Sildenafil Citrate and Dapoxetine into a single tablet, this treatment offers a comprehensive approach to improving sexual performance, confidence, and relationship satisfaction. It is manufactured under strict pharmaceutical standards to ensure efficacy, safety, and reliability for men seeking a dual-therapy solution.

Features

• Active ingredients: Sildenafil Citrate (100mg) and Dapoxetine Hydrochloride (160mg)
• Tablet form, film-coated for ease of swallowing
• Rapid onset of action, typically within 30–60 minutes
• Duration of effect: up to 4–6 hours for erectile support; up to 3–4 hours for ejaculatory control
• Manufactured in FDA-approved facilities following GMP guidelines
• Available in blister packs of 10 tablets

Benefits

• Achieve and maintain firmer, more reliable erections suitable for sexual activity
• Significantly prolong intravaginal ejaculatory latency time, enhancing sexual endurance
• Improve overall sexual satisfaction for both partners
• Boost self-confidence and reduce anxiety related to sexual performance
• Convenient single-tablet regimen reduces pill burden and simplifies treatment
• Supports healthier intimate relationships through improved sexual function

Common use

Malegra FXT Plus is prescribed for adult men experiencing both erectile dysfunction (ED) and premature ejaculation (PE). It is suitable for individuals who have not achieved desired results with monotherapies targeting either condition alone. Typical users include men with organic, psychogenic, or mixed etiology ED accompanied by lifelong or acquired PE. It is intended for use prior to anticipated sexual activity and is not recommended for daily dosing.

Dosage and direction

The recommended dosage is one tablet taken orally approximately 1–3 hours before sexual activity. Swallow the tablet whole with a full glass of water; do not crush, chew, or break. This medication requires sexual stimulation to be effective. Avoid high-fat meals before administration, as they may delay onset of action. Do not exceed one dose within a 24-hour period. Dosage adjustments may be necessary based on individual tolerance and response, under medical supervision.

Precautions

• Not for use by women, children, or adolescents under 18 years
• Avoid alcohol consumption, as it may increase side effects and decrease efficacy
• Use with caution in patients with cardiovascular risk factors; sexual activity poses potential cardiac risk
• Not recommended for men with anatomical penile deformities or conditions predisposing to priapism
• Caution advised in patients with history of seizures, bipolar disorder, or orthostatic hypotension
• Regular monitoring of blood pressure may be required during treatment
• Discontinue use and seek medical attention if erection persists beyond 4 hours

Contraindications

• Hypersensitivity to Sildenafil, Dapoxetine, or any component of the formulation
• Concurrent use of nitrates or nitric oxide donors in any form
• Patients with severe cardiovascular, hepatic, or renal impairment
• History of non-arteritic anterior ischemic optic neuropathy (NAION)
• Retinitis pigmentosa or other hereditary retinal disorders
• Concurrent administration with strong CYP3A4 inhibitors or monoamine oxidase inhibitors (MAOIs)
• Uncontrolled hypertension or hypotension

Possible side effects

Common side effects (usually mild to moderate and transient) may include:

• Headache, dizziness, flushing
• Nasal congestion, dyspepsia
• Nausea, diarrhea
• Insomnia, fatigue
• Visual disturbances (bluish tint, blurred vision)
• Increased sweating

Less common but serious side effects requiring immediate medical attention:

• Priapism (prolonged, painful erection)
• Severe hypotension, syncope
• Serotonin syndrome symptoms (agitation, hallucinations, tachycardia)
• Sudden hearing or vision loss
• Seizures, arrhythmias

Drug interaction

Malegra FXT Plus has significant interaction potential:

• Absolute contraindication with nitrates (e.g., nitroglycerin, isosorbide) due to risk of severe hypotension
• Avoid concomitant use with alpha-blockers (e.g., doxazosin, tamsulosin)
• Increased risk of serotonin syndrome with SSRIs, SNRIs, tricyclic antidepressants, or triptans
• Potent CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) may increase plasma concentrations
• CYP3A4 inducers (e.g., rifampin, carbamazepine) may reduce efficacy
• Grapefruit juice may increase bioavailability and side effects
• Use caution with other antihypertensives due to additive hypotensive effects

Missed dose

Malegra FXT Plus is not intended for regular scheduled dosing. If a dose is missed or not taken within the appropriate pre-coital window, simply resume with the next planned sexual activity. Do not double the dose to make up for a missed administration. Consistent timing relative to anticipated sexual activity is more important than maintaining a strict dosing schedule.

Overdose

Symptoms of overdose may include severe hypotension, syncope, prolonged erection, serotonin syndrome, or cardiovascular events. In case of suspected overdose, seek immediate medical attention. Symptomatic and supportive care is indicated; priapism may require urgent urological intervention. Hemodialysis is not expected to significantly enhance elimination due to high protein binding.

Storage

Store at room temperature (15–30°C) in original packaging, protected from light and moisture. Keep out of reach of children and pets. Do not use after expiration date printed on packaging. Do not transfer tablets to alternative containers, as exposure to air and humidity may degrade active ingredients.

Disclaimer

This product requires a valid prescription from a licensed healthcare provider. This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment. Always consult your physician before starting, changing, or discontinuing any medication. Individual results may vary; not all users will experience the described benefits. Use only as directed under medical supervision.

Reviews

Clinical studies demonstrate that combination therapy with Sildenafil and Dapoxetine provides significantly greater improvement in IIEF and IELT scores compared to placebo or monotherapy. Patients report enhanced sexual satisfaction and reduced distress related to sexual performance. Most adverse events were mild and self-limiting, with discontinuation rates below 5% in phase III trials. Real-world evidence supports its efficacy and tolerability in appropriately selected patients.